Summary. This is a rare condition for which there is a European and/or American orphan designation. This term designates an indication for a pharmacogenetic. Necrotizing enterocolitis (NEC) is an acquired condition of diffuse necrotic injury to the mucosal and submucosal layers of the bowel. It is the most serious. Transcript of Enterocolite Necrotizante. Pneumatose intestinal. Pneumatose intestinal. DIAGNÓSTICO – Incidência de por RN vivos – Predominio em .
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Necrotising enterocolitis NEC is the most common gastrointestinal condition in premature neonates. It is characterised by inflammation, ischemia, and permeability of the neonatal bowel wall to bacteria.
It is potentially life-threatening with significant associated morbidity 1. NEC is usually idiopathic and multi-factorial.
A combination of ischemic and infective etiology with added contributive factors such as immature immunity necrotiizante been proposed 1. Although a partially infective etiology has been hypothesised, no causative organism has been isolated. Translocation of intestinal flora through immature mucosa has been postulated 5.
Inflammation starts from the mucosal surface and progresses to hemorrhagic and coagulative necrosis.
There is ensuing loss of mucosal integrity, transmural necrosis, and perforation. Although NEC can affect any part of the large or small bowel, the most necrotizannte location is the terminal ileum.
The right colon including cecum is occasionally involved. Involvement of the stomach is less common. Supine abdominal x-rays are the mainstay of diagnosis. NEC can be managed both medically and surgically and appropriate patient selection is essential in optimising outcome. Enterocolitf clinical staging system has been developed see necrotising enterocolitis stagingwith stage I and II receiving medical therapy and stage III undergoing surgery 8.
Medical management consists of supportive measures and cessation of oral feeding, along with broad-spectrum antibiotics and gastric aspiration 7. Surgery is usually reserved for patients with evidence of enterocolife and entails resection of clearly necrotic bowel and the creation of a proximal enterostomy Other relative indications for surgery include portal venous gasa fixed dilated loop on serial x-rays and abdominal wall erythema 7.
Re-anastomosis is usually delayed until the infant has completely recovered. In the correct clinical scenario, the presence of gas within bowel wall has a entercolite differential. Conditions worth keeping in mind include You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Unable to process the form.
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Enterocolite necrotizante – Wikipédia, a enciclopédia livre
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